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Sexually transmitted infections (STIs) are infections that are primarily spread through sexual contact. Common STIs include chlamydia, gonorrhea, syphilis, HIV, herpes, and HPV. STIs can have serious health consequences if left untreated, including infertility, chronic pain, and increased risk of certain types of cancer. The best way to prevent STIs is to practice safe sex, such as using condoms, getting tested regularly, and being open and honest with sexual partners.